Cecil Walker III and Joe DiTullio (The Third and The Don) make their picks for week five of the NFL football season. Their season totals are tallied at the bottom of the table.
| Away Team | Home Team | Joe | Cecil |
| Arizona Cardinals | San Francisco 49ers | Cardinals | Cardinals |
| New England Patriots | Cleveland Browns | Patriots | Patriots |
| Philadelphia Eagles | Detroit Lions | Eagles | Lions |
| Chicago Bears | Indianaspolis Colts | Colts | Colts |
| Tennessee Titans | Miami Dolphins | Dolphins | Dolphins |
| Washington Redskins | Baltimore Ravens | Ravens | Redskins |
| Houston Texans | Minnesota Vikings | Vikings | Vikings |
| New York Jets | Pittsburgh Steelers | Steelers | Steelers |
| Atlanta Falcons | Denver Broncos | Broncos | Broncos |
| Cincinnati Bengals | Dallas Cowboys | Cowboys | Cowboys |
| Buffalo Bills | Los Angeles Rams | Rams | Rams |
| San Diego Chargers | Oakland Raiders | Raiders | Chargers |
| New York Giants | Green Bay Packers | Packers | Packers |
| Tampa Bay Bucs | Carolina Panthers | Panthers | Panthers |
| Season Total | 40 | 38 |