Rob Doerger and Joe DiTullio (personalities on the DiTullio and Doerger College Sports Show) pick every game including an FBS team in week five.
| Away | Home | Location | Rob | Joe |
| Connecticut | #6 Houston | TDECU Stadium, Houston, TX | Houston | Houston |
| Kansas | Texas Tech | Jones AT&T Stadium, Lubbock, TX | Texas Tech | TTU |
| #7 Stanford | #10 Washington | Husky Stadium, Seattle, WA | Stanford | Stanford |
| Toledo | BYU | LaVell Edwards Stadium, Provo, UT | BYU | BYU |
| Notre Dame | Syracuse | MetLife Stadium, East Rutherford, NJ | Notre Dame | Notre Dame |
| Alcorn State | #20 Arkansas | War Memorial Stadium , Little Rock, AR | Arkansas | Arkansas |
| #13 Baylor | Iowa State | Jack Trice Stadium, Ames, IA | Baylor | Baylor |
| #23 Florida | Vanderbilt | Vanderbilt Stadium, Nashville, TN | Florida | Florida |
| #22 Texas | Oklahoma State | Boone Pickens Stadium, Stillwater, OK | OK State | Ok St |
| Rutgers | #2 Ohio State | Ohio Stadium, Columbus, OH | OSU | OSU |
| Margin of Victory | 42 | 35 | ||
| Northwestern | Iowa | Kinnick Stadium, Iowa City, IA | Iowa | Iowa |
| UCF | East Carolina | Dowdy-Ficklen Stadium, Greenville, NC | ECU | ECU |
| SMU | Temple | Lincoln Financial Field, Philadelphia, PA | Temple | Temple |
| #14 Miami | Georgia Tech | Bobby Dodd Stadium, Atlanta, GA | Miami | Miami |
| Georgia State | Appalachian State | Kidd Brewer Stadium, Boone, NC | App St | App St |
| Virginia | Duke | Wallace Wade Stadium, Durham, NC | Duke | Duke |
| Buffalo | Boston College | Alumni Stadium , Chestnut Hill, MA | BC | BC |
| Oregon State | Colorado | Folsom Field, Boulder, CO | Colorado | Colorado |
| Ohio | Miami (OH) | Yager Stadium, Oxford, OH | Ohio | Ohio |
| Eastern Michigan | Bowling Green | Doyt Perry Stadium, Bowling Green, OH | BG | BG |
| Navy | Air Force | Falcon Stadium, Usaf Academy, CO | Air Force | AF |
| Louisiana Monroe | Auburn | Jordan-Hare Stadium, Auburn, AL | Auburn | Auburn |
| #11 Tennessee | #25 Georgia | Sanford Stadium, Athens, GA | Georgia | Tennessee |
| Tulane | Massachusetts | Warren McGuirk Alumni Stadium, Amherst, MA | Umass | Umass |
| Northern Illinois | Ball State | Scheumann Stadium, Muncie, IN | Ball St | Ball St |
| North Carolina | #12 Florida State | Doak Campbell Stadium, Tallahassee, FL | FSU | FSU |
| Wake Forest | NC State | Carter-Finley Stadium, Raleigh, NC | Wake | NC State |
| Akron | Kent State | Dix Stadium, Kent, OH | Akron | Akron |
| Purdue | Maryland | Maryland Stadium, College Park, MD | Maryland | Maryland |
| #8 Wisconsin | #4 Michigan | Michigan Stadium, Ann Arbor, MI | Michigan | Michigan |
| Illinois | #15 Nebraska | Memorial Stadium , Lincoln, NE | Nebraska | Nebraska |
| Minnesota | Penn State | Beaver Stadium, University Park, PA | Penn St | Penn St |
| Kansas State | West Virginia | Milan Puskar Stadium, Morgantown, WV | WVU | WVU |
| #9 Texas A&M | South Carolina | Williams-Brice Stadium, Columbia, SC | A&M | TAMU |
| San José State | New Mexico | University Stadium , Albuquerque, NM | San Jose St | SJSU |
| Oklahoma | #21 TCU | Amon G. Carter Stadium, Fort Worth, TX | Oklahoma | Oklahoma |
| Troy | Idaho | Kibbie Dome, Moscow, ID | Idaho | Idaho |
| Old Dominion | Charlotte | McColl-Richardson Field, Charlotte, NC | ODU | ODU |
| #18 Utah | California | Memorial Stadium , Berkeley, CA | Cal | Utah |
| Memphis | #16 Ole Miss | Vaught-Hemingway Stadium, Oxford, MS | Ole Miss | Ole miss |
| Kentucky | #1 Alabama | Bryant-Denny Stadium, Tuscaloosa, AL | Alabama | Bama |
| Florida Atlantic | Florida Intl | FIU Stadium, Miami, FL | FIU | FIU |
| UTEP | Louisiana Tech | Joe Aillet Stadium, Ruston, LA | LT | LT |
| Middle Tennessee | North Texas | Apogee Stadium, Denton, TX | MTSU | MTSU |
| Rice | Southern Mississippi | M. M. Roberts Stadium, Hattiesburg, MS | So Miss | So Miss |
| Houston Baptist | Western Kentucky | L.T. Smith Stadium, Bowling Green, KY | WKU | WKU |
| South Florida | Cincinnati | Nippert Stadium, Cincinnati, OH | USF | USF |
| Western Michigan | Central Michigan | Kelly/Shorts Stadium, Mount Pleasant, MI | W. Mich | WMU |
| Incarnate Word | Texas State | Bobcat Stadium , San Marcos, TX | Texas St | Texas St |
| Marshall | Pittsburgh | Heinz Field, Pittsburgh, PA | Pitt | Pitt |
| Missouri | LSU | Tiger Stadium , Baton Rouge, LA | Mizzou | LSU |
| #3 Louisville | #5 Clemson | Memorial Stadium , Clemson, SC | Clemson | Louisville |
| #19 San Diego State | South Alabama | Ladd-Peebles Stadium, Mobile, AL | San Diego St | SDSU |
| Louisiana Lafayette | New Mexico State | Aggie Memorial Stadium, Las Cruces, NM | ULL | ULL |
| #17 Michigan State | Indiana | Memorial Stadium , Bloomington, IN | Mich St | MSU |
| Arizona State | USC | Los Angeles Memorial Coliseum, Los Angeles, CA | Arizona St | USC |
| Oregon | Washington State | Martin Stadium, Pullman, WA | Wash St | Wazzu |
| Utah State | #24 Boise State | Albertsons Stadium, Boise, ID | Boise | Boise |
| Wyoming | Colorado State | Hughes Stadium , Fort Collins, CO | Colorado St | Colorado State |
| Fresno State | UNLV | Sam Boyd Stadium, Las Vegas, NV | UNLV | UNLV |
| Arizona | UCLA | Rose Bowl, Pasadena, CA | UCLA | UCLA |
| Nevada | Hawai’i | Aloha Stadium, Honolulu, HI | Hawai’i | Nevada |
| Gameday Guest Picker (Clemson, SC) | Brian Dawkins | Dwight Clark | ||
| Season Totals | 243 | 235 |