Joe DiTullio and Rob Doerger continue their season long picks of every FBS college football game for week 7. Here are the picks:
| Away | Home | Location | Rob | Joe |
| Texas State | Louisiana | Cajun Field, Lafayette, LA | ULL | ULL |
| #2 Clemson | Syracuse | Carrier Dome, Syracuse, NY | Clemson | Clemson |
| #8 Washington State | California | Memorial Stadium , Berkeley, CA | Wash St | Washington State |
| #6 TCU | Kansas State | Bill Snyder Family Stadium, Manhattan, KS | TCU | TCU |
| #17 Michigan | Indiana | Memorial Stadium , Bloomington, IN | Michigan | Michigan |
| #20 NC State | Pittsburgh | Heinz Field, Pittsburgh, PA | NC State | NC State |
| #24 Texas Tech | West Virginia | Milan Puskar Stadium, Morgantown, WV | Texas Tech | West Virginia |
| Florida State | Duke | Wallace Wade Stadium, Durham, NC | FSU | FSU |
| Rutgers | Illinois | Memorial Stadium , Champaign, IL | Illini | Illinois |
| Eastern Michigan | Army | Michie Stadium, West Point, NY | Army | Army |
| BYU | Mississippi State | Davis Wade Stadium, Starkville, MS | Miss St | Miss State |
| South Carolina | Tennessee | Neyland Stadium, Knoxville, TN | Tennessee | South Carolina |
| Kansas | Iowa State | Jack Trice Stadium, Ames, IA | Iowa St | Iowa State |
| Connecticut | Temple | Lincoln Financial Field, Philadelphia, PA | Temple | Temple |
| Boston College | Louisville | Papa John’s Cardinal Stadium, Louisville, KY | Louisville | Louisville |
| UNLV | Air Force | Falcon Stadium, Usaf Academy, CO | Air Force | AF |
| Old Dominion | Marshall | Joan C. Edwards Stadium, Huntington, WV | Marshall | Marshall |
| Purdue | #7 Wisconsin | Camp Randall Stadium, Madison, WI | Wisconsin | Wisconsin |
| #10 Auburn | LSU | Tiger Stadium , Baton Rouge, LA | Auburn | Auburn |
| Georgia Tech | #11 Miami | Hard Rock Stadium, Miami, FL | Miami | Georgia Tech |
| #12 Oklahoma | Texas | Cotton Bowl, Dallas, TX | Oklahoma | Oklahoma |
| Baylor | #14 Oklahoma State | Boone Pickens Stadium, Stillwater, OK | OK St | Ok St |
| Virginia | North Carolina | Kenan Stadium, Chapel Hill, NC | Uva | UVA |
| Northwestern | Maryland | Maryland Stadium, College Park, MD | Maryland | Northwestern |
| Vanderbilt | Ole Miss | Vaught-Hemingway Stadium, Oxford, MS | Vandy | Vandy |
| Akron | Western Michigan | Waldo Stadium, Kalamazoo, MI | WMU | WMU |
| Miami (OH) | Kent State | Dix Stadium, Kent, OH | Miami (OH) | Miami |
| Northern Illinois | Buffalo | UB Stadium, Buffalo, NY | NIU | NIU |
| Ohio | Bowling Green | Doyt Perry Stadium, Bowling Green, OH | Ohio | Ohio |
| Toledo | Central Michigan | Kelly/Shorts Stadium, Mount Pleasant, MI | Toledo | Toledo |
| #25 Navy | Memphis | Liberty Bowl Memorial Stadium, Memphis, TN | Memphis | Memphis |
| Houston | Tulsa | Chapman Stadium, Tulsa, OK | Houston | Houston |
| Colorado | Oregon State | Reser Stadium, Corvallis, OR | Colorado | Colorado |
| Charlotte | Western Kentucky | L.T. Smith Stadium, Bowling Green, KY | WKU | WKU |
| Wyoming | Utah State | Romney Stadium, Logan, UT | Utah St | Utah St |
| Georgia State | Louisiana Monroe | Malone Stadium, Monroe, LA | ULM | ULM |
| Appalachian State | Idaho | Kibbie Dome, Moscow, ID | App St | App St |
| New Mexico State | Georgia Southern | Allen E. Paulson Stadium, Statesboro, GA | NMSU | NMSU |
| Middle Tennessee | UAB | Legion Field , Birmingham, AL | MTSU | MTSU |
| East Carolina | #22 UCF | Spectrum Stadium, Orlando, FL | UCF | UCF |
| Margin of victory | 36 | 25 | ||
| UT San Antonio | North Texas | Apogee Stadium, Denton, TX | UNT | UTSA |
| UTEP | Southern Mississippi | M. M. Roberts Stadium, Hattiesburg, MS | USM | USM |
| Tulane | Florida Intl | FIU Stadium, Miami, FL | Tulane | Tulane |
| Texas A&M | Florida | Ben Hill Griffin Stadium, Gainesville, FL | Florida | TAMU |
| Coastal Carolina | Arkansas State | Centennial Bank Stadium, Jonesboro, AR | Ark St | Ark State |
| Arkansas | #1 Alabama | Bryant-Denny Stadium, Tuscaloosa, AL | Bama | Bama |
| Missouri | #4 Georgia | Sanford Stadium, Athens, GA | Georgia | UGA |
| #9 Ohio State | Nebraska | Memorial Stadium , Lincoln, NE | OSU | OSU |
| Cincinnati | #18 South Florida | Raymond James Stadium, Tampa, FL | USF | USF |
| Utah | #13 USC | Los Angeles Memorial Coliseum, Los Angeles, CA | USC | USC |
| #21 Michigan State | Minnesota | TCF Bank Stadium, Minneapolis, MN | Mich St | Mich ST |
| UCLA | Arizona | Arizona Stadium, Tucson, AZ | Arizona | Arizona |
| New Mexico | Fresno State | Bulldog Stadium , Fresno, CA | Fresno | Fresno |
| Nevada | Colorado State | CSU Stadium, Fort Collins, CO | Col St | Col St |
| Boise State | #19 San Diego State | SDCCU Stadium, San Diego, CA | SDSU | SDSU |
| #5 Washington | Arizona State | Sun Devil Stadium, Tempe, AZ | Washington | Washington |
| Oregon | #23 Stanford | Stanford Stadium, Stanford, CA | Stanford | Stanford |
| San José State | Hawai’i | Aloha Stadium, Honolulu, HI | Hawaii | Hawaii |
| Villanova | James Madison | James Madison | James Madison | |
| Gameday Guest Picker (Harrisonburg, VA) | Lindsey Czarniak | Phil Vassar |
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