Cecil Walker and Joe DiTullio (personalities on The Third and The Don Football Show) make their picks for week two of the college football season.
| Away Team | Home Team | Joe | Cecil |
| New York Jets | Buffalo Bills | Jets | Jets |
| Cincinnati Bengals | Pittsburgh Steelers | Steelers | Bengals |
| Tennessee Titans | Detroit Lions | Lions | Titans (UPSET PICK) |
| Baltimore Ravens | Cleveland Browns | Ravens | Ravens |
| Dallas Cowboys | Washington Redskins | Cowboys | Cowboys |
| New Orleans Saints | New York Giants | Giants | Giants |
| San Francisco 49ers | Carolina Panthers | Panthers | Panthers |
| Miami Dolphins | New England Patriots | Patriots | Patriots |
| Kansas City Chiefs | Houston Texans | Chiefs | Texans |
| Seattle Seahawks | Los Angeles Rams | Seahawks | Seahawks |
| Tampa Bay Bucs | Arizona Cardinals | Cardinals | Cardinals |
| Jacksonville Jaguars | San Diego Chargers | Jaguars | Jaguars |
| Atlanta Falcons | Oakland Raiders | Falcons | Raiders |
| Indianapolis Colts | Denver Broncos | Broncos | Broncos |
| Green Bay Packers | Minnesota Vikings (2 points) | Packers | Packers |
| Philadelphia Eagles | Chicago Bears (2 points) | Bears | Bears |