Cecil Walker and Joe DiTullio of the Third and The Don Football Show will make their picks every week of the NFL season. These are straight-up picks. Here are the NFL Week 8 Picks.
| Away | Home | Location | Cecil | Joe |
| Washington | Minnesota | U.S. Bank Stadium, Minneapolis | Vikings | Vikings |
| Seattle | Atlanta | Mercedes-Benz Stadium, Atlanta | Seahawks | Seahawks |
| Philadelphia | Buffalo | New Era Field, Buffalo | Bills | Bills |
| Los Angeles Chargers | Chicago | Soldier Field, Chicago | Bears | Bears |
| New York Giants | Detroit | Ford Field, Detroit | Lions | Lions |
| Tampa Bay | Tennessee | Nissan Stadium, Nashville | Titans | Bucs |
| Denver | Indianapolis | Lucas Oil Stadium, Indianapolis | Colts | Colts |
| Cincinnati | Los Angeles Rams | Wembley Stadium, London | Rams | Rams |
| Arizona | New Orleans | Mercedes-Benz Superdome, New Orleans | Saints | Saints |
| New York Jets | Jacksonville | TIAA Bank Field, Jacksonville | Jags | Jags |
| Carolina | San Francisco | Levi’s Stadium, Santa Clara | Panthers | 49ers |
| Cleveland | New England | Gillette Stadium, Foxboro | Patriots | Patriots |
| Oakland | Houston | NRG Stadium, Houston | Texans | Texans |
| Green Bay | Kansas City | Arrowhead Stadium, Kansas City | Packers | Packers |
| Miami | Pittsburgh | Heinz Field, Pittsburgh | Steelers | Steelers |
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