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NFL Week 7 Picks Against the Spread

NFL Week 7 Picks Against the Spread

Publish Date: October 20, 2026

The NFL season is here. Picking NFL games straight up is hard enough, but picking against the spread is even tougher. Here are NFL week 7 picks against the spread. (Spreads are from Tallysight as of Tuesday morning)

Last week: 5-9

Season: 42-46-4

Thursday Night Football

New England Patriots at Chicago Bears (-2.5)

The Bears’ offense came back to life with Caleb Williams back from injury. They had problems closing out the game late against the Falcons, but can clean them up. Drake Maye is playing well, but may have trouble keeping up with the Bears.

Pick: Bears

Sunday Morning

Pittsburgh Steelers (-3.5) at New Orleans Saints (Game in Paris, France)

Pittsburgh has the offense rolling, but so does New Orleans at this point. While the Steelers’ defense has the edge and may get them the win in Paris, New Orleans can likely keep it close, as they are averaging 25.3 points per game.

Pick: Saints

Sunday Afternoon

Indianapolis Colts at Minnesota Vikings (-6)

The Colts are a mess right now, especially defensively. Minnesota’s defense is the best in the league, which gives them plenty of cushion to cover the spread at home.

Pick: Vikings

Tampa Bay Buccaneers at Carolina Panthers (-3.5)

Baker Mayfield is trying to return this week, but that will be determined by his grip on the football. If he can’t play, the Panthers are the obvious pick. Even if he can play, his grip on the football could make things difficult. With Bryce Young playing well this season, they can win and cover at home.

Pick: Panthers

Miami Dolphins at New York Jets (-4.5)

While the Dolphins are coming off a bye, the Jets have the more well-balanced team. Their defense can limit the Dolphins and the offense can help them win by a touchdown, especially after getting Omar Cooper Jr. back from injury, which helped the offense.

Pick: Jets

New York Giants at Houston Texans (-9.5)

The Giants were able to come back late against the Saints, but looked bad for most of the game. Houston is starting to put some wins together and the defense still hasn’t even reached their potential. This could be a game where the defense really steps up and gets them back in playoff contention talks early in the season.

Pick: Texans

Cincinnati Bengals at Baltimore Ravens (-3)

Lamar Jackson has been out for a couple of weeks and is not confirmed to return. Even if he does, he will be rusty. The Bengals are coming off a bye and the defense is much better than last season. They can go on the road and pull off the upset.

Pick: Bengals

San Francisco 49ers (-3.5) at Atlanta Falcons 

San Francisco looks like the best team in the league. For the most part, they are winning games by comfortable margins, despite their injuries. Their closest game was a three-point win over Seattle on the road. They should be able to beat the Falcons by a bit more.

Pick: 49ers

Cleveland Browns (-2) at Tennessee Titans

The Browns got more offensive output a few weeks ago, but have scored just 12.5 points per game over their last two. Tennessee has a solid defense to limit the Browns and the offense showed signs of life against the Colts. It’s a coin flip game, so taking the home team could be the right call.

Pick: Titans

Sunday Evening

Denver Broncos (-4.5) at Arizona Cardinals

Denver had extra time to prepare for this game after playing on Thursday Night Football in Week 6. The defense will travel and should be able to limit the Cardinals. Arizona did beat the Rams last week, but might come back to reality this week.

Pick: Broncos

Green Bay Packers at Detroit Lions (-3)

This game should be a shootout. Detroit can be more balanced offensively, while the Packers can still struggle to run the ball. The Lions are coming off a bye, so they will have an edge in this game.

Pick: Lions

Los Angeles Rams (-4.5) at Las Vegas Raiders

The Rams are not playing up to their potential and need to win this game to get things back on the right track. Las Vegas has lost three straight games and that streak will likely continue, but the Rams need to really clean some things up, and do well without Davante Adams to do it.

Pick: Rams

Sunday Night Football

Kansas City Chiefs at Seattle Seahawks (-2.5)

Seattle is not getting great play from the quarterback position this season. Kansas City has had solid defense play and the offense has hit a new level with Kenneth Walker III leading the running game. Walker III can have a revenge game and help his team pull off the win on the road.

Pick: Chiefs

Monday Night Football

Dallas Cowboys (-4.5) at Philadelphia Eagles

The Eagles will be without Jalen Hurts for the season and the offense already didn’t look great. Dallas has had plenty of issues, specifically on defense, but this is exactly what the doctor ordered. They can win and cover on the road to get things rolling.

Pick: Cowboys

 

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