Home » NFL Week 6 Picks Against the Spread

NFL Week 6 Picks Against the Spread

Publish Date: October 12, 2021

NFL Week 6 is here. Picking NFL games straight up is hard enough, but picking against the spread is even tougher. Here are the NFL week 6 picks against the spread. (Spreads are from tallysight as of Tuesday morning)

Last week: 9-7, Season total: 38-41-1

Thursday Night Football

Tampa Bay Buccaneers (-6.5) at Philadelphia Eagles

The Buccaneers have shown that they can roll right through inferior competition if the weather is nice. Tom Brady and the Bucs’ offense will be too much for the Eagles to keep up with, even if they are having issues in their secondary.

Pick: Buccaneers

Sunday Morning

Miami Dolphins (-3.5) vs. Jacksonville Jaguars *In London

Jacksonville looks like a team that doesn’t believe in their coach. That is understandable given the circumstances. Add that to the fact that the Jaguars have a rookie quarterback making a trip across the pond and the Dolphins should win and cover.

Pick: Dolphins

Sunday Afternoon

Los Angeles Chargers at Baltimore Ravens (-3.5)

This is a cross-country game for the Chargers, but they do get an extra day of rest than the Ravens. Baltimore needed a miraculous comeback to beat the Colts and the Chargers are playing much better than them right now.

Pick: Chargers

Minnesota Vikings at Carolina Panthers (-1.5)

Are the Panthers going to do what happened last year by starting off the year strong then fading down the stretch? Maybe. They should have Christian McCaffrey back for this one, which helps greatly. Minnesota has been close in every game this season and this is one they can win.

Pick:Vikings

Green Bay Packers (-4.5) at Chicago Bears

The Bears are still getting quarterback Justin Fields quality reps and he will be playing in this game hurt. Even with a running game that is playing well, Aaron Rodgers will be able to cover against a rookie quarterback.

Pick: Packers

Cincinnati Bengals (-3.5) at Detroit Lions

Detroit is playing teams tough and have come up short. They will eventually get a win, but it will likely come randomly. The Bengals’ defense has been playing well enough for them to cover against the Lions on the road. Their playcalling needs to improve and this may be the game they let Joe Burrow air it out.

Pick: Bengals

Houston Texans at Indianapolis Colts (-10.5)

The Texans, for the most part, have been keeping things close. That may change against the Colts, who have a solid defense and are starting to feed Jonathan Taylor the ball. Indianapolis should win and cover at home.

Pick: Colts

Los Angeles Rams (-10.5) at New York Giants

The Giants have so many injuries on their offense right now that they won’t be able to keep up with the Rams. Wide receivers are hurt, Saquon Barkley will likely miss the game and Daniel Jones is in the concussion protocol. The Rams shouldn’t have too many issues.

Pick: Rams

Kansas City Chiefs (-6.5) at Washington Football Team

Kansas City has struggled against the spread recently. That should change this week as oddsmakers are reacting to that. The Chiefs should be able to go on the road and defeat Washington with how bad their defense is playing.

Pick: Chiefs

Sunday Evening

Arizona Cardinals at Cleveland Browns (-2.5)

Kyler Murray has the Cardinals as the only remaining undefeated team in the league. Arizona should win a high-scoring game much like the Chargers did against the Browns in week 5.

Pick: Cardinals

Las Vegas Raiders at Denver Broncos (-3.5)

The Raiders will have a new coach for this week, which will likely make things difficult. Denver has the home-field advantage and the better defense, so they should be able to win and cover.

Pick: Broncos

Dallas Cowboys (-4.5) at New England Patriots

This line is disrespectful to what the Cowboys have done this season. The Cowboys have too many weapons for a defense to cover and their own defense is forcing turnovers every game. Against a rookie quarterback who doesn’t have many weapons, they should win by at least a touchdown or two.

Pick: Cowboys

Sunday Night Football

Seattle Seahawks at Pittsburgh Steelers (-4.5)

Seattle will be without Russell Wilson for this game. The Steelers will be able to pressure Geno Smith into mistakes to win and cover at home.

Pick: Steelers

Monday Night Football

Buffalo Bills (-4.5) at Tennessee Titans 

Buffalo will have a tall task in slowing down Derrick Henry, but the Bills are playing on another level since week 1. Tennessee will not be able to stop Josh Allen and will lose by a touchdown at home.

Pick: Bills

Go to our NFL page for more articles and updates like NFL week 6 Picks Against the Spread!

You can like The Game Haus on Facebook and follow us on Twitter for more sports and esports articles from great TGH writers!

Leave A Reply

* required
Read Also
Top-25 Offensive Free Agent Predictions for the 2022 NFL Offseason
It’s been a little over a month since the Los Angeles Rams ...
Realistic Quarterback Options for the Tampa Bay Buccaneers
It became official Tuesday morning, Tampa Bay Buccaneers quarterback Tom Brady has ...
NFL Head Coaching Candidates for the 2022 Season
Now that the NFL regular season has concluded the NFL's head coaching ...
Predicting Each NFL Team’s Over/Under
Before the season, sportsbooks will release a number of wins they predict ...
Top-25 NFL Offensive Free Agent Predictions for the 2021 Season
It's been a little over two weeks since the Tampa Bay Buccaneers ...
The Game Haus aims to bring unbiased, factually sound opinions to audiences across a range of mediums that are not readily accessible in the day-to-day media outlets. We cover the latest news in Gaming, Call of Duty, CS:GO, League of Legends, Dota 2, Fighting Games, NBA 2K, Halo, Hearthstone, Overwatch, Pokemon, Rocket League, Smite, Starcraft II, Fantasy Sports, MLS, EPL, MLB, NASCAR, NBA, NCAAB, NCAAF, NFL, NHL, and PGA.


Next to our unbiased coverage for esports and sports, have a look at our iGaming content. If you are looking for the most recommended Esports Betting Sites or Best Sports Betting Sites, look no further. We also cover the Best Sweepstakes Casinos in our free 2 play section and have a closer look at the Best DFS Sites out there. If you are looking for some real money options, check how we ranked the Best Online Casinos.


Follow us on Social Media for updates!
Sports: Facebook | Twitter
Esports: Facebook | Twitter

Players must be 21 years of age or older or reach the minimum age for gambling in their respective state and located in jurisdictions where online gambling is legal. Please play responsibly. Bet with your head, not over it. If you or someone you know has a gambling problem, and wants help, call or visit: (a) the Council on Compulsive Gambling of New Jersey at 1-800-Gambler or www.800gambler.org; or (b) Gamblers Anonymous at 855-2-CALL-GA or www.gamblersanonymous.org.

×
Your Promo Code:
The bonus offer of was already opened in an additional window. If not, you can open it also by clicking the following link:
Play now