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Fantasy Football Week 6 Running Back Rankings

Joe Mixon

The 2021-22 NFL season has already been extremely entertaining. Bye weeks are starting to take place. This means that quarterbacks like Alvin Kamara and Cordarrelle Patterson will be out this week. On top of that injuries have started to mount up at this point of the season. It is always a great idea to evaluate backup options so that way fantasy managers are prepared if star players miss time. Here are the fantasy football week 6 quarterback rankings.

*Ratings are subject to change due to injury reports or possible move to reserve/COVID-19 list*

(Check out the section below for details on players already rumored to possibly miss this week and how their replacement options rank for the week)

Must Start- a player who is in your lineup regardless of the matchup or most circumstances. They Will likely finish near the top of the league in points that week and in most weeks.
Starting RB1- a player who makes fantasy owners comfortable starting week after week. Regardless of the matchup, this player has a high floor.
High-End RB2- a player who may isn’t likely to carry a lineup that week, but has the ability to have a breakout game and is teetering between RB1 and RB2 category.
Starting RB2- a player who should be started in most lineups and should reach their point projection. This player is started is because of their consistency and moderately high floor
Low RB2- a player who may not be a lock to start for a team every week, but will start more times than not. Their production may not be pretty or win a person their lineup but the production is consistent enough to make a fantasy owner comfortable starting them.
Flex- a player who could float around the territory of being benched, but is started due to the potential to play better than their point projection. However, this player has the potential to flop and causes a fantasy team to lose if he has a bad game.
Deep League Flex- a player who is more of a Hail Mary throw at the position. There are enough reasons to leave this player on the bench, but their upside makes them an attractive option. Desperate times may call for a player like this to be inserted into starting lineups.
Leave on the Bench- a player who should be avoided in all lineups that week. Many times this player could even be left on waivers.
Must StartChristian McCaffrey*vs Minnesota VikingsRB1
Must StartAustin Ekelervs Baltimore RavensRB2
Must StartDalvin Cook*vs Carolina PanthersRB3
Must StartDerrick Henryvs Buffalo BillsRB4
Starting RB1Najee Harrisvs Seattle SeahawksRB5
Starting RB1Jonathan Taylorvs Houston TexansRB6
Starting RB1Darrell Hendersonvs New York GiantsRB7
Starting RB1James Robinsonvs Tennessee TitansRB8
High-End RB2Antonio Gibsonvs Kansas City ChiefsRB9
High-End RB2Ezekiel Elliott*vs New England PatriotsRB10
High-End RB2Aaron Jonesvs Chicago BearsRB11
High-End RB2Kareem Huntvs Arizona CardinalsRB12
Starting RB2D’Andre Swiftvs Cincinnati BengalsRB13
Starting RB2Joe Mixonvs Detriot LionsRB14
Starting RB2Nick Chubbvs Arizona CardinalsRB15
Starting RB2Damien Williamsvs Green Bay PackersRB16
Low RB2Leonard Fournettevs Philadelphia EaglesRB17
Low RB2Myles Gaskinvs Jacksonville JaguarsRB18
Low RB2Devontae Bookervs Los Angeles RamsRB19
Low RB2Zack Mossvs Tennessee TitansRB20
Low RB2Devontae Bookervs Los Angeles RamsRB21
Low RB2Chase Edmondsvs Cleveland BrownsRB22
FlexMelvin Gordonvs Las Vegas RaidersRB23
FlexDarrel Williamsvs Washinton Football TeamRB24
FlexChris Carson*vs Pittsburgh SteelersRB25
FlexJosh Jacobsvs Denver BroncosRB26
FlexJamaal Williamsvs Cincinnati BengalsRB27
Deep League FlexJavonte Williamsvs Las Vegas RaidersRB28
Deep League FlexDamien Harris*vs Dallas CowboysRB29
Deep League FlexLatavius Murrayvs Los Angeles ChargersRB30
Deep League FlexBrandon Boldenvs Dallas CowboysRB31
Deep League FlexJames Connervs Cleveland BrownsRB32
Deep League FlexMiles Sandersvs Tampa Bay BuccaneersRB33
Deep League FlexTony Pollardvs New England PatriotsRB34
Deep League FlexKhalil Herbertvs Green Bay PackersRB35
Deep League FlexKenneth Gainwellvs Tampa Bay BuccaneersRB36
Deep League FlexJ.D. McKissicvs Kansas City ChiefsRB37
Deep League FlexMark Ingramvs Indianapolis ColtsRB38
Deep League FlexA.J. Dillonvs Chicago BearsRB39
Deep League FlexNyheim Hinesvs Houston TexansRB40
Deep League FlexDavid Johnsonvs Indianapolis ColtsRB41
Deep League Flex Jerick McKinnonvs Washington Football TeamRB42
Leave on the BenchGiovanni Bernardvs Philadelphia EaglesRB43
Leave on the BenchSony Michelvs New York GiantsRB44
Leave on the BenchSamaje Perine*vs Detriot LionsRB45
Leave on the BenchDevin Singletaryvs Tennessee TitansRB46
Leave on the BenchAlex Collinsvs Pittsburgh SteelersRB47
Leave on the BenchMarlon Mackvs Houston TexansRB48
Leave on the BenchCarlos Hydevs Miami DolphinsRB49
Leave on the BenchJeremy McNicholsvs Buffalo BillsRB50
Leave on the BenchDevonta Smithvs Los Angeles ChargersRB51
Leave on the BenchMalcolm Brownvs Jacksonville JaguarsRB52
Leave on the BenchRonald Jonesvs Philadelphia EaglesRB53
Leave on the BenchRhamondre Stevensonvs Dallas CowboysRB54
Leave on the BenchKenyan Drakevs Denver BroncosRB55
Leave on the BenchChuba Hubbardvs Minnesota VikingsRB56
Leave on the BenchSalvon Ahmedvs Jacksonville JaguarsRB57
Leave on the BenchPhillip Lindsayvs Indianapolis ColtsRB58
Leave on the BenchTy’Son Williamsvs Los Angeles ChargersRB59
Leave on the BenchChris Evansvs Detriot LionsRB60
Leave on the BenchDeejay Dallasvs Pittsburgh SteelersRB61
Leave on the BenchAlexander Mattisonvs Carolina PanthersRB62
Leave on the BenchTravis Homervs Pittsburgh SteelersRB63
Leave on the BenchJaret Pattersonvs Kansas City ChiefsRB64
Leave on the BenchDemetric Feltonvs Arizona CardinalsRB65

Possible Changes that can occur before Sunday

RB1 Christian McCaffrey, Carolina Panthers

Even though Christian McCaffrey returned to practice last week he still missed last week’s game against the Philadelphia Eagles. He is questionable for this week’s game against the Vikings. If McCaffrey were to miss another game Chuba Hubbard would move up to RB18 between Myles Gaskin and Devontae Booker.

RB3 Dalvin Cook, Minnesota Vikings

Dalvin Cook was a late inactive last week against the Lions after trying out his ankle to see if he could play in it. Depending on how practice goes this week Cook could miss another game to try to play. If Cook is inactive Alexander Mattison moves up to RB11 between Aaron Jones and Kareem Hunt.

RB10 Ezekiel Elliott, Dallas Cowboys

Ezekiel Elliott hurt his lower back in the win last week against the New York Giants. He should be good to play but this is something to monitor throughout the week. If Elliott were to miss this week Tony Pollard would become the RB14 between Joe Mixon and Nick Chubb.

RB25 Chris Carson, Seattle Seahawks

Seahawks’ running back Chris Carson missed last Thursday’s game against the Pittsburgh Steelers with a neck injury. He has made progress and could be ready by this weekend. However, if Carson was to miss another game Alex Collins would move up to RB26 between Josh Jacobs

RB29 Damien Harris, New England Patriots

Last week Damien Harris left the game against the Texans with a chest injury. It is uncertain whether this injury is severe enough to hold Harris out this week against the Dallas Cowboys. If Harris misses this week Brandon Bolden would jump up to Harris’ spot at RB20 and Rhamondre Stevenson would move up to RB35 between Tony Pollard and Khalil Herbert.

RB45 Samaje Perine, Cincinnati Bengals

Bengals running back Samaje Perine was added to the reserve/COVID-19 list on Monday after testing positive for COVID-19. If Perine doesn’t play expect Chris Evans to be the Bengals’ change of pace back this weekend.


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