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Fantasy Football Week 6 Quarterback Rankings

Fantasy Football Week 6 Quarterback Rankings

Publish Date: October 8, 2025



The 2025-26 NFL season is underway which means we are in the thick of fantasy football season! The fantasy landscape has already changed since the preseason due to breakout players and major injuries across the league. Bye weeks are starting to take place. This means that quarterbacks like C.J. Stroud and Carson Wentz will be out this week. It would be irresponsible to start a player with a rough matchup over a player with a more favorable one that is ranked or projected to perform similarly. Here are fantasy football Week 6 quarterback rankings.

[Ratings are subject to change due to injury reports or possible move to Injured Reserve List]

[Check out the section below for details on players already rumored to possibly miss this week and how their replacement options rank for the week]

Key:

Must Start- a player who should definitely be in your lineup that week because of the combination of matchup and talent. They will likely finish near the top of the league in points that week and could repeat the production most weeks.

Starter- a player who makes fantasy owners comfortable starting week after week. Regardless of the matchup, this player has a high floor.

Low-End Starter- a player who should be started in most lineups but can possibly bottom out and finish below average on a given week. A high ceiling play in two-quarterback or superflex leagues.

Streamer- a player who could be a perfect replacement for a starter for a week or two. Starting this player may not win you your lineup but they will make sure that your production out of that position will not lose you your matchup either. Also a viable option in two-quarterback or superflex leagues.

Deep League Streamer- a player who could fill a void at a position in a deeper league. Their ceiling may be close to average point production at the position but their floor is enough to get through the week. A reasonable player to have in your lineup in two-quarterback or superflex leagues.

Leave on the Bench- a player who should be avoided in all lineups that week. Many times this player could even be left on waivers.

Fantasy Football Week 6 Quarterback Rankings

CategoryNameOpponentRanking
Must StartJosh Allenvs Atlanta FalconsQB1
Must StartLamar Jackson*vs Los Angeles RamsQB2
Must StartJayden Danielsvs Chicago BearsQB3
Must StartJalen Hurtsvs New York GiantsQB4
StarterPatrick Mahomesvs Detroit LionsQB5
StarterJustin Herbertvs Miami DolphinsQB6
StarterBaker Mayfieldvs San Francisco 49ersQB7
StarterBo Nixvs New York JetsQB8
StarterCaleb Williamsvs Washington CommandersQB9
Low-End StarterMatthew Staffordvs Baltimore RavensQB10
Low-End StarterJordan Lovevs Cincinnati BengalsQB11
Low-End StarterBrock Purdy*vs Tampa Bay BuccaneersQB12
Low-End StarterDrake Mayevs New Orleans SaintsQB13
Low-End StarterDak Prescottvs Carolina PanthersQB14
Low-End StarterKyler Murray*vs Indiananapolis ColtsQB15
StreamerDaniel Jonesvs Arizona CardinalsQB16
StreamerJustin Fieldsvs Denver BroncosQB17
StreamerJared Goffvs Kansas City ChiefsQB18
StreamerSam Darnoldvs Jacksonville JaguarsQB19
Deep League StreamerTrevor Lawerencevs Seattle SeahawksQB20
Deep League StreamerBryce Youngvs Dallas CowboysQB21
Deep League StreamerTua Tagovailoavs Los Angeles ChargersQB22
Leave on the BenchSpencer Rattlervs New England PatriotsQB23
Leave on the BenchGeno Smithvs Tennessee TitansQB24
Leave on the BenchJaxson Dartvs Philadelphia EaglesQB25
Leave on the BenchMichael Penixvs Arizona CardinalsQB26
Leave on the BenchAaron Rodgersvs Cleveland BrownsQB27
Leave on the BenchDillion Gabrielvs Pittsburgh SteelersQB28
Leave on the BenchCam Wardvs Las Vegas RaidersQB29
Leave on the BenchJoe Flaccovs Green Bay PackersQB30

Possible Changes that can occur before Sunday

QB2 Lamar Jackson, Baltimore Ravens

Lamar Jackson missed last week’s game against the Houston Texans with a hamstring injury. There is a slim chance that Jackson returns this week. If Jackson misses Week 6 against the Los Angeles Rams Cooper Rush becomes the QB30 below Joe Flacco.

QB12 Brock Purdy, San Francisco 49ers

Brock Purdy missed last week’s game against the Los Angeles Rams. He is currently considered week-to-week and could return this week. If Purdy misses Week 6 against the Tampa Bay Buccaneers Mac Jones becomes QB19 between Sam Darnold and Trevor Lawerence.

QB15 Kyler Murray, Arizona Cardinals

Kyler Murray suffered a foot injury last week against the Tennessee Titans. Arizona is going to “see how this week goes” when it comes to Murray’s status for this week. If Murray misses Week 6 against the Indianapolis Colts Jacoby Brissett becomes QB3O below Joe Flacco.

Players that are currently not expected to play

Jake Browning, Cincinnati Bengals

On Tuesday the Cincinnati Bengals traded a fifth round pick for Joe Flacco and a sixth round pick. This comes one day after announcing that they will consider other options at quarterback. Browning has arguably been the worst quarterback in the league to play for an extended period of time this season. Cincinnati will likely start Flacco over Browning this week. Flacco should provide a higher floor for this offense until Joe Burrow returns. He is unlikely to be fantasy relevant based of the play he had earlier this season in Cleveland.

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