The 2021-22 NFL season has only four weeks left. Bye weeks are over which means the fantasy playoffs have begun in most standard leagues. This time of year COVID-19 is running rampant which makes it important to have backup options on your fantasy roster. On top of that injuries are continuing to mount up. It is always a great idea to evaluate backup options so that way fantasy managers are prepared if star players miss time. Here are the Fantasy Football Week 15 running back rankings.
*Ratings are subject to change due to injury reports or possible move to reserve/COVID-19 list*
(Check out the section below for details on players already rumored to possibly miss this week and how their replacement options rank for the week)
| Category | Name | Opponent | Ranking |
| Must Start | Jonathan Taylor | vs New England Patriots | RB1 |
| Must Start | Dalvin Cook | vs Chicago Bears | RB2 |
| Must Start | Austin Ekeler | vs Kansas City Chiefs | RB3 |
| Starting RB1 | Nick Chubb | vs Las Vegas Raiders | RB4 |
| Starting RB1 | Alvin Kamara | vs Tampa Bay Buccaneers | RB5 |
| Starting RB1 | Najee Harris | vs Tennessee Titans | RB6 |
| Starting RB1 | Joe Mixon | vs Denver Broncos | RB7 |
| Starting RB1 | Cordarrelle Patterson | vs San Francisco 49ers | RB8 |
| High-End RB2 | David Montgomery | vs Minnesota Vikings | RB9 |
| High-End RB2 | Antonio Gibson | vs Philadelphia Eagles | RB10 |
| High-End RB2 | Darrell Henderson* | vs Seattle Seahawks | RB11 |
| Starting RB2 | Ezekiel Elliott | vs New York Giants | RB12 |
| Starting RB2 | Leonard Fournette* | vs New Orleans Saints | RB13 |
| Starting RB2 | Elijah Mitchell* | vs Atlanta Falcons | RB14 |
| Starting RB2 | James Conner* | vs Detroit Lions | RB15 |
| Starting RB2 | Javonte Williams* | vs Cincinnati Bengals | RB16 |
| Starting RB2 | James Robinson | vs Houston Texans | RB17 |
| Starting RB2 | Chase Edmonds* | vs Detroit Lions | RB18 |
| Low RB2 | Aaron Jones | vs Baltimore Ravens | RB19 |
| Low RB2 | Myles Gaskin* | vs New York Jets | RB20 |
| Low RB2 | Saquon Barkley | vs Dallas Cowboys | RB21 |
| Low RB2 | Damien Harris* | vs Indianapolis Colts | RB22 |
| Flex | Devonta Freeman | vs Green Bay Packers | RB23 |
| Flex | A.J. Dillon | vs Baltimore Ravens | RB24 |
| Flex | Michael Carter* | vs Miami Dolphins | RB25 |
| Flex | Rashaad Penny | vs Los Angeles Rams | RB26 |
| Flex | D’onta Foreman | vs Pittsburgh Steelers | RB27 |
| Flex | Melvin Gordon | vs Cincinnati Bengals | RB28 |
| Flex | Jamaal Williams* | vs Arizona Cardinals | RB29 |
| Deep League Flex | Darrel Williams | vs Los Angeles Chargers | RB30 |
| Deep League Flex | Tony Pollard* | vs New York Giants | RB31 |
| Deep League Flex | Chuba Hubbard | vs Buffalo Bills | RB32 |
| Deep League Flex | J.D. McKissic* | vs Philadelphia Eagles | RB33 |
| Deep League Flex | Rhamondre Stevenson | vs Indianapolis Colts | RB34 |
| Deep League Flex | Miles Sanders* | vs Washington Football Team | RB35 |
| Deep League Flex | Dontrell Hilliard | vs Pittsburgh Steelers | RB36 |
| Deep League Flex | Mike Davis | vs San Francisco 49ers | RB37 |
| Deep League Flex | Devin Singletary | vs Carolina Panthers | RB38 |
| Deep League Flex | David Johnson | vs Jacksonville Jaguars | RB39 |
| Deep League Flex | Sony Michel | vs Seattle Seahawks | RB40 |
| Deep League Flex | D’Ernest Johnson | vs Las Vegas Raiders | RB41 |
| Leave on the Bench | Brandon Bolden | vs Indianapolis Colts | RB42 |
| Leave on the Bench | Ameer Abdullah | vs Buffalo Bills | RB43 |
| Leave on the Bench | Royce Freeman | vs Jacksonville Jaguars | RB44 |
| Leave on the Bench | Jeremy McNichols | vs Pittsburgh Steelers | RB45 |
| Leave on the Bench | Jordan Howard* | vs Washington Football Team | RB46 |
| Leave on the Bench | Matt Breida | vs Carolina Panthers | RB47 |
| Leave on the Bench | Craig Reynolds | vs Arizona Cardinals | RB48 |
| Leave on the Bench | Mark Ingram* | vs Tampa Bay Buccaneers | RB49 |
| Leave on the Bench | Boston Scott | vs Washington Football Team | RB50 |
| Leave on the Bench | Devontae Booker | vs Dallas Cowboys | RB51 |
| Leave on the Bench | Godwin Igwebuike | vs Arizona Cardinals | RB52 |
| Leave on the Bench | Carlos Hyde* | vs Houston Texans | RB53 |
| Leave on the Bench | Samaje Perine | vs Denver Broncos | RB54 |
| Leave on the Bench | Alex Collins* | vs Los Angeles Rams | RB55 |
| Leave on the Bench | Tevin Coleman* | vs Miami Dolphins | RB56 |
| Leave on the Bench | Salvon Ahmed* | vs New York Jets | RB57 |
| Leave on the Bench | Latavius Murray | vs Green Bay Packers | RB58 |
| Leave on the Bench | Kenneth Gainwell | vs Washington Football Team | RB59 |
| Leave on the Bench | Ty Johnson | vs Miami Dolphins | RB60 |
| Leave on the Bench | Jeff Wilson Jr. | vs Atlanta Falcons | RB61 |
| Leave on the Bench | Alexander Mattison* | vs Chicago Bears | RB62 |
| Leave on the Bench | Zack Moss | vs Carolina Panthers | RB63 |
| Leave on the Bench | Phillip Lindsay* | vs New York Jets | RB64 |
| Leave on the Bench | Adrian Peterson | vs Los Angeles Rams | RB65 |
| Leave on the Bench | Kyle Juszczyk | vs Atlanta Falcons | RB66 |
| Leave on the Bench | Nyheim Hines | vs New England Patriots | RB67 |
| Leave on the Bench | Travis Homer | vs Los Angeles Rams | RB68 |
| Leave on the Bench | Justin Jackson | vs Kansas City Chiefs | RB69 |
| Leave on the Bench | Jermar Jefferson | vs Arizona Cardinals | RB70 |
| Leave on the Bench | Joshua Kelley | vs Kansas City Chiefs | RB71 |
| Leave on the Bench | Duke Johnson Jr. | vs New York Jets | RB72 |
Darrell Henderson was inactive last week because he was added to the Reserve/COVID-19 list. If he was to miss this week’s game against the Seattle Seahawks then Sony Michel would move up to RB16 between Javonte Williams and James Robinson.
Leonard Fournette missed practice Wednesday with a sore ankle. They brought in Kenjon Barner to ensure they had depth. Giovanni Bernard is on injured reserve. If Fournette was to miss this week against the New Orleans Saints then Ronald Jones would become the RB29 between Jamaal Williams and Darrel Williams.
Elijah Mitchell missed last week’s game against the Cincinnati Bengals because he was still in concussion protocol. If Mitchell was to miss this week’s game against the Atlanta Falcons then Jeff Wilson Jr. would become the RB22 between Damien Harris and Devonta Freeman.
The Arizona Cardinals activated Chase Edmonds from injured reserve last week. Edmonds has missed the last four games (five weeks) with a high ankle sprain. Late last week against the Los Angles Rams James Conner suffered an ankle injury. That ankle injury held Conner out of practice Wednesday. If both are inactive this week against the Detroit Lions then Eno Benjamin would join the list at RB20 between Saquon Barkley and Damien Harris.
If the Cardinals decide to not activate Edmonds and Conner plays then Conner would move up to RB6 between Alvin Kamara and Najee Harris.
If the Cardinals activate Edmonds and Conner plays then Edmonds would move up to RB13 between Ezekiel Eliott and Leonard Fournette.
Javonte Williams was limited in practice with a knee injury. If he was to miss this week’s game against the Cincinnati Bengals then Melvin Gordon would move up to RB18 between Chase Edmonds and Aaron Jones.
The Miami Dolphins running back room is all dealing with COVID-19. All of Myles Gaskins, Salvon Ahmed, and Phillip Lindsay are on the Reserve/COVID-19 list. This is something fantasy managers must pay attention to throughout the week. If none are activated Sunday before the New York Jets then Duke Johnson Jr. moves up to RB24 between A.J. Dillon and Michael Carter.
Damien Harris was limited with a hamstring injury he has been dealing with since New England’s last game which was the Monday night game before their bye against Buffalo. If he was to miss this week’s game against the Indianapolis Colts then Rhamondre Stevenson would move up to RB20 between Aaron Jones and Myles Gaskin.
Shortly before their game last week against the Denver Broncos the Detroit Lions place Jamaal Williams on the Reserve/COVID-19 list. It is unclear whether Williams will return this week against the Arizona Cardinals. If Williams was to miss another game then Craig Reynolds would move up to RB33 between J.D. McKissic and Rhamondre Stevenson. Godwin Igwebuike would move up to RB43 between Brandon Bolden and Ameer Abdullah. Jermar Jefferson would also move up to RB66 between Kyle Juszczyk and Nyheim Hines.
Tony Pollard is dealing with a torn plantar fascia (foot injury). He missed last week’s game against the Washington Football Team. If Pollard cannot play then veterans Corey Clement should complement Ezekiel Elliott this weekend against the New York Giants
J.D. McKissic missed the past two weeks with a concussion. If he was to miss this week against the Philadelphia Eagles then Antonio Gibson should see more work on passing downs and Wendell Smallwood could be the change-of-pace back.
After their bye the Philadephia Eagles’ top two running backs are dealing with injuries. Miles Sanders was limited in practice with an ankle injury and Jordan Howard was limited with a knee issue. If both miss this week’s game against the Washington Football Team then Boston Scott would take over Sanders’ RB35 slot.
If Sanders was inactive and Howard was active then Howard would move up to RB32 between Tony Pollard and Chuba Hubbard, Boston Scott would then move up to RB45 between Royce Freeman and Jeremy McNichols.
If Sanders was active and Howard was inactive then Sanders would stay the RB35 and Boston Scott would move up to RB45 between Royce Freeman and Jeremy McNichols.
Mark Ingram missed last week’s game against the New York Jets because he was placed on the Reserve/COVID-19 list. If he was to miss this week’s game against the Tampa Bay Buccaneers then Tony Jones Jr. would become the RB55 between Alex Collins and Tevin Coleman.
Carlos Hyde missed practice Wednesday because of a concussion. If he was to miss this week’s game against the Houston Texans then James Robinson would be solidified as the RB17 and Dare Ogunbowale would be his backup.
The Seattle Seahawks placed running back Alex Collins on the Reserve/COVID-19 list Thursday. If he was to miss this week’s game against the Los Angeles Rams then Rashaad Penny retains his value at RB26 and Adrian Peterson moves up to Collins’ RB55 slot. Travis Homer and DeeJay Dallas could get work for Seattle this weekend as well.
Tevin Coleman missed last week’s game against the New Orleans Saints with a concussion. If he was to miss this week’s game against the Miami Dolphins then Ty Johnson would jump into Coleman’s RB56 slot.
Alexander Mattison has been placed on the Reserve/COVID-19 list by the Minnesota Vikings. If Mattison was to miss this week’s game against the Chicago Bears Kene Nwangwu would jump into Mattison’s role for this offense and his slot at RB62.
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