Rob Doerger and Joe DiTullio (staff writers and podcast personalities on The DiTullio and Doerger College Sports Show) give their picks for week two of the college football season.
| Away | Home | Location | Rob | Joe |
| Maryland | Florida Intl | FIU Stadium, Miami, FL | Maryland | Maryland |
| #13 Louisville | Syracuse | Carrier Dome, Syracuse, NY | Louisville | Louisville |
| Central Michigan | #22 Oklahoma State | Boone Pickens Stadium, Stillwater, OK | OK State | Ok St |
| NC State | East Carolina | Dowdy-Ficklen Stadium, Greenville, NC | ECU | NC State |
| Penn State | Pittsburgh | Heinz Field, Pittsburgh, PA | Penn St | Pitt |
| UCF | #5 Michigan | Michigan Stadium, Ann Arbor, MI | Michigan | Michigan |
| Margin of Victory (1 point) | 50 | 42 | ||
| Cincinnati | Purdue | Ross-Ade Stadium, West Lafayette, IN | Purdue | Cincy |
| Lamar | #6 Houston | TDECU Stadium, Houston, TX | Houston | Houston |
| Howard | Rutgers | High Point Solutions Stadium, Piscataway, NJ | Rutgers | Rutgers |
| Indiana State | Minnesota | TCF Bank Stadium, Minneapolis, MN | Minnesota | Minnesota |
| Rice | Army | Michie Stadium, West Point, NY | Army | Army |
| Boston College | Massachusetts | Gillette Stadium, Foxboro, MA | BC | BC |
| Nicholls State | #9 Georgia | Sanford Stadium, Athens, GA | Georgia | Georgia |
| Prairie View A&M | Texas A&M | Kyle Field, College Station, TX | A&M | TAMU |
| Wyoming | Nebraska | Memorial Stadium , Lincoln, NE | Nebraska | Nebraska |
| Charleston Southern | #3 Florida State | Doak Campbell Stadium, Tallahassee, FL | FSU | FSU |
| Troy | #2 Clemson | Memorial Stadium , Clemson, SC | Clemson | Clemson |
| Stony Brook | Temple | Lincoln Financial Field, Philadelphia, PA | Temple | Temple |
| Georgia State | Air Force | Falcon Stadium, Usaf Academy, CO | Air Force | AF |
| Utah State | USC | Los Angeles Memorial Coliseum, Los Angeles, CA | USC | USC |
| Youngstown State | West Virginia | Milan Puskar Stadium, Morgantown, WV | WVU | WVU |
| Ohio | Kansas | Memorial Stadium , Lawrence, KS | Ohio | Ohio |
| Mercer | Georgia Tech | Bobby Dodd Stadium, Atlanta, GA | GT | GT |
| North Dakota | Bowling Green | Doyt Perry Stadium, Bowling Green, OH | Bowling Green | BG |
| Connecticut | Navy | Navy-Marine Corps Memorial Stadium, Annapolis, MD | Navy | Navy |
| Illinois State | Northwestern | Ryan Field, Evanston, IL | NW | NW |
| Tulsa | #4 Ohio State | Ohio Stadium, Columbus, OH | OSU | OSU |
| Eastern Illinois | Miami (OH) | Yager Stadium, Oxford, OH | Miami (OH) | Miami |
| Wake Forest | Duke | Wallace Wade Stadium, Durham, NC | Duke | Duke |
| Old Dominion | Appalachian State | Kidd Brewer Stadium, Boone, NC | App St | App State |
| Akron | Wisconsin | Camp Randall Stadium, Madison, WI | Buzzcuts (Wisconsin) | Wisconsin |
| Nevada | #18 Notre Dame | Notre Dame Stadium, Notre Dame, IN | ND | ND |
| Kentucky | Florida | Ben Hill Griffin Stadium, Gainesville, FL | Kentucky | Kentucky |
| Western Kentucky | #1 Alabama | Bryant-Denny Stadium, Tuscaloosa, AL | Bama | Bama |
| SMU | #23 Baylor | McLane Stadium, Waco, TX | Baylor | Baylor |
| Wofford | #19 Ole Miss | Vaught-Hemingway Stadium, Oxford, MS | Ole Miss | Ole Miss |
| Ball State | Indiana | Memorial Stadium , Bloomington, IN | Indiana | Indiana |
| Texas San Antonio | Colorado State | Hughes Stadium , Fort Collins, CO | Colorado St | CSU |
| Middle Tennessee | Vanderbilt | Vanderbilt Stadium, Nashville, TN | MTSU | MTSU |
| Portland State | San José State | CEFCU Stadium – Home of the Spartans, San Jose, CA | San Jose St | SJSU |
| Idaho | #8 Washington | Husky Stadium, Seattle, WA | Washington | Washington |
| Idaho State | Colorado | Folsom Field, Boulder, CO | Colorado | Colorado |
| Morgan State | Marshall | Joan C. Edwards Stadium, Huntington, WV | Marshall | Marshall |
| Elon | Charlotte | McColl-Richardson Field, Charlotte, NC | Charlotte | Charlotte |
| North Carolina A&T | Kent State | Dix Stadium, Kent, OH | Kent St | Kent State |
| Florida Atlantic | #25 Miami | Hard Rock Stadium, Miami, FL | Miami | Miami |
| Georgia Southern | South Alabama | Ladd-Peebles Stadium, Mobile, AL | Georgia Southern | USA |
| McNeese State | Louisiana Lafayette | Cajun Field, Lafayette, LA | ULL | ULL |
| Louisiana Monroe | #14 Oklahoma | Memorial Stadium , Norman, OK | Oklahoma | Oklahoma |
| North Carolina Central | Western Michigan | Waldo Stadium, Kalamazoo, MI | WMU | WMU |
| Maine | Toledo | Glass Bowl, Toledo, OH | Toledo | Toledo |
| Northern Illinois | South Florida | Raymond James Stadium, Tampa, FL | USF | USF |
| Bethune-Cookman | North Texas | Apogee Stadium, Denton, TX | NT | NT |
| South Carolina State | Louisiana Tech | Joe Aillet Stadium, Ruston, LA | LT | LT |
| Savannah State | Southern Mississippi | M. M. Roberts Stadium, Hattiesburg, MS | S. Miss | So Miss |
| UTEP | #11 Texas | Royal Texas Memorial Stadium, Austin, TX | Texas | Texas |
| South Carolina | Mississippi State | Davis Wade Stadium, Starkville, MS | Miss St | South Carolina |
| Arkansas | #15 TCU | Amon G. Carter Stadium, Fort Worth, TX | TCU | TCU |
| Arkansas State | Auburn | Jordan-Hare Stadium, Auburn, AL | Auburn | Auburn |
| Iowa State | #16 Iowa | Kinnick Stadium, Iowa City, IA | Iowa | Iowa |
| BYU | Utah | Rice-Eccles Stadium, Salt Lake City, UT | Utah | BYU |
| Eastern Michigan | Missouri | Memorial Stadium/Faurot Field, Columbia, MO | Mizzou | Mizzou |
| Jacksonville State | #21 LSU | Tiger Stadium , Baton Rouge, LA | LSU | LSU |
| North Carolina | Illinois | Memorial Stadium , Champaign, IL | UNC-CH | UNC |
| Southern | Tulane | Yulman Stadium, New Orleans, LA | Tulane | Tulane |
| Virginia Tech | #17 Tennessee | Bristol Motor Speedway, Bristol, TN (5 points) | Tennessee | Tennessee |
| UNLV | UCLA | Rose Bowl, Pasadena, CA | UCLA | UCLA |
| New Mexico | New Mexico State | Aggie Memorial Stadium, Las Cruces, NM | New Mexico | NM |
| Sacramento State | Fresno State | Bulldog Stadium , Fresno, CA | Fresno | Fresno |
| Texas Tech | Arizona State | Sun Devil Stadium, Tempe, AZ | Arizona St | Texas Tech |
| Washington State | Boise State | Albertsons Stadium, Boise, ID | Wash St | Boise |
| California | San Diego State | Qualcomm Stadium, San Diego, CA | San Diego St | SDSU |
| Virginia | #24 Oregon | Autzen Stadium, Eugene, OR | Oregon | Oregon |
| Grambling State | Arizona | Arizona Stadium, Tucson, AZ | Arizona | Zona |
| Tennessee-Martin | Hawai’i | Aloha Stadium, Honolulu, HI | Hawai’i | Hawaii |
| Gameday Guest Picker (Bristol, TN) (10 Points) | Kenny Chesney | Peyton Manning | ||
| Season Total | 79 | 70 |
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