Joe DiTullio and Rob Doerger make their college football picks for week eight including all games that include FBS teams.
| Away | Home | Location | Rob | Joe |
| Louisiana | Arkansas State | Centennial Bank Stadium, Jonesboro, AR | Ark St | Ark St |
| #25 Memphis | Houston | TDECU Stadium, Houston, TX | Memphis | Memphis |
| Western Kentucky | Old Dominion | S.B. Ballard Stadium, Norfolk, VA | WKU | WKU |
| Marshall | Middle Tennessee | Floyd Stadium, Murfreesboro, TN | Marshall | Marshall |
| Air Force | Nevada | Mackay Stadium, Reno, NV | Air Force | AF |
| Colorado State | New Mexico | Dreamstyle Stadium, Albuquerque, NM | Col St | Col St |
| Maryland | #5 Wisconsin | Camp Randall Stadium, Madison, WI | Wisconsin | Wisconsin |
| #10 Oklahoma State | Texas | Royal Texas Memorial Stadium, Austin, TX | OK State | Ok St |
| Tulsa | Connecticut | Rentschler Field, East Hartford, CT | Tulsa | Tulsa |
| Akron | Toledo | Glass Bowl, Toledo, OH | Toledo | Toledo |
| Iowa | Northwestern | Ryan Field, Evanston, IL | Iowa | NW |
| Purdue | Rutgers | High Point Solutions Stadium, Piscataway, NJ | Purdue | Purdue |
| Louisville | Florida State | Doak Campbell Stadium, Tallahassee, FL | Fla St | FSU |
| Idaho | Missouri | Memorial Stadium/Faurot Field, Columbia, MO | Mizzou | Mizzou |
| Iowa State | Texas Tech | Jones AT&T Stadium, Lubbock, TX | TTU | TTU |
| Temple | Army | Michie Stadium, West Point, NY | Army | Army |
| Pittsburgh | Duke | Wallace Wade Stadium, Durham, NC | Duke | Duke |
| Boston College | Virginia | Scott Stadium, Charlottesville, VA | Uva | UVA |
| Troy | Georgia State | Georgia State Stadium, Atlanta, GA | Troy | Troy |
| Kent State | Ohio | Peden Stadium, Athens, OH | Ohio | Ohio |
| Northern Illinois | Bowling Green | Doyt Perry Stadium, Bowling Green, OH | NIU | NIU |
| Western Michigan | Eastern Michigan | Rynearson Stadium, Ypsilanti, MI | EMU | WMU |
| Buffalo | Miami (OH) | Yager Stadium, Oxford, OH | Buffalo | Miami |
| Central Michigan | Ball State | Scheumann Stadium, Muncie, IN | CMU | CMU |
| Tennessee | #1 Alabama | Bryant-Denny Stadium, Tuscaloosa, AL | Alabama | Alabama |
| Syracuse | #8 Miami | Hard Rock Stadium, Miami, FL | Miami | Miami |
| North Carolina | #14 Virginia Tech | Lane Stadium, Blacksburg, VA | VT | VT |
| Indiana | #18 Michigan State | Spartan Stadium , East Lansing, MI | Mich St | MSU |
| #20 UCF | Navy | Navy-Marine Corps Memorial Stadium, Annapolis, MD | UCF | UCF |
| Coastal Carolina | Appalachian State | Kidd Brewer Stadium, Boone, NC | App St | App St |
| Georgia Southern | UMass | Warren McGuirk Alumni Stadium, Amherst, MA | Umass | Umass |
| Arizona State | Utah | Rice-Eccles Stadium, Salt Lake City, UT | Arizona St | ASU |
| Illinois | Minnesota | TCF Bank Stadium, Minneapolis, MN | Minnesota | Minnesota |
| #9 Oklahoma | Kansas State | Bill Snyder Family Stadium, Manhattan, KS | Oklahoma | Oklahoma |
| Kentucky | Mississippi State | Davis Wade Stadium, Starkville, MS | Miss St | Miss St |
| Oregon | UCLA | Rose Bowl, Pasadena, CA | UCLA | UCLA |
| SMU | Cincinnati | Nippert Stadium, Cincinnati, OH | SMU | SMU |
| Louisiana Monroe | South Alabama | Ladd-Peebles Stadium, Mobile, AL | USA | USA |
| North Texas | Florida Atlantic | FAU Football Stadium, Boca Raton, FL | N. Texas | N Texas |
| Utah State | UNLV | Sam Boyd Stadium, Las Vegas, NV | Utah St | Utah St |
| UAB | Charlotte | McColl-Richardson Field, Charlotte, NC | UAB | UAB |
| #16 South Florida | Tulane | Yulman Stadium, New Orleans, LA | USF | USF |
| Southern Mississippi | Louisiana Tech | Joe Aillet Stadium, Ruston, LA | USM | USM |
| Rice | UT San Antonio | Alamodome, San Antonio, TX | UTSA | UTSA |
| BYU | East Carolina | Dowdy-Ficklen Stadium, Greenville, NC | BYU | BYU |
| #24 LSU | Ole Miss | Vaught-Hemingway Stadium, Oxford, MS | LSU | LSU |
| #19 Michigan | #2 Penn State | Beaver Stadium, University Park, PA | Penn St | Penn St |
| #11 USC | #13 Notre Dame | Notre Dame Stadium, Notre Dame, IN | ND | USC |
| #21 Auburn | Arkansas | Razorback Stadium, Fayetteville, AR | Auburn | Auburn |
| Wake Forest | Georgia Tech | Bobby Dodd Stadium, Atlanta, GA | GT | GT |
| Kansas | #4 TCU | Amon G. Carter Stadium, Fort Worth, TX | TCU | TCU |
| Margin of Victory | 30 | 34 | ||
| #23 West Virginia | Baylor | McLane Stadium, Waco, TX | WVU | WVU |
| Arizona | California | Memorial Stadium , Berkeley, CA | Arizona | Arizona |
| Wyoming | Boise State | Albertsons Stadium, Boise, ID | Boise | Boise |
| Fresno State | San Diego State | SDCCU Stadium, San Diego, CA | SDSU | SDSU |
| Colorado | #15 Washington St | Martin Stadium, Pullman, WA | Wash St | Wazzu |
| Gameday Guest Picker (University Park) | Ty Burrell | Lisa Salters |
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