The first two weeks of college football have had some surprises and big games to go along with a hurricane causing games to be cancelled. Rob Doerger and Joe DiTullio continue their picks for every single FBS college football game. Here are the week three picks:
| Away | Home | Location | Rob | Joe |
| New Mexico | Boise State | Albertsons Stadium, Boise, ID | Boise | Boise |
| Illinois | #22 South Florida | Raymond James Stadium, Tampa, FL | Illinois | USF |
| UMass | Temple | Lincoln Financial Field, Philadelphia, PA | Temple | Temple |
| Arizona | UTEP | Sun Bowl, El Paso, TX | Arizona | Zona |
| Air Force | #7 Michigan | Michigan Stadium, Ann Arbor, MI | Michigan | Michigan |
| #9 Oklahoma State | Pittsburgh | Heinz Field, Pittsburgh, PA | OK State | Ok State |
| #25 UCLA | Memphis | Liberty Bowl Memorial Stadium, Memphis, TN | Memphis | UCLA |
| Northern Illinois | Nebraska | Memorial Stadium , Lincoln, NE | Nebraska | Nebraska |
| Louisiana | Texas A&M | Kyle Field, College Station, TX | Texas A&M | TAMU |
| Kansas | Ohio | Peden Stadium, Athens, OH | Ohio | Ohio |
| Delaware State | West Virginia | Milan Puskar Stadium, Morgantown, WV | WVU | WVU |
| Iowa State | Akron | InfoCision Stadium, Akron, OH | Iowa St | ISU |
| Connecticut | Virginia | Scott Stadium, Charlottesville, VA | Uva | UVA |
| Furman | NC State | Carter-Finley Stadium, Raleigh, NC | NC State | NC State |
| Baylor | Duke | Wallace Wade Stadium, Durham, NC | Duke | Duke |
| Coastal Carolina | UAB | Legion Field , Birmingham, AL | Coastal | Coastal |
| Northern Colorado | Colorado | Folsom Field, Boulder, CO | Colorado | Colorado |
| Utah State | Wake Forest | BB&T Field, Winston-salem, NC | Wake | Wake |
| Tennessee Tech | Ball State | Scheumann Stadium, Muncie, IN | Ball St | Ball St |
| #10 Wisconsin | BYU | LaVell Edwards Stadium, Provo, UT | Wisconsin | Wisconsin |
| #16 Virginia Tech | East Carolina | Dowdy-Ficklen Stadium, Greenville, NC | VT | Va Tech |
| SMU | #20 TCU | Amon G. Carter Stadium, Fort Worth, TX | TCU | TCU |
| #23 Tennessee | #24 Florida | Ben Hill Griffin Stadium, Gainesville, FL | Tennessee | Florida |
| Central Michigan | Syracuse | Carrier Dome, Syracuse, NY | C. Mich | Syracuse |
| North Carolina | Old Dominion | S.B. Ballard Stadium, Norfolk, VA | Old Dom | UNC |
| Notre Dame | Boston College | Alumni Stadium , Chestnut Hill, MA | ND | ND |
| Morgan State | Rutgers | High Point Solutions Stadium, Piscataway, NJ | Rutgers | Rutgers |
| Middle Tennessee | Minnesota | TCF Bank Stadium, Minneapolis, MN | Minnesota | Minnesota |
| Florida Intl | Indiana | Memorial Stadium , Bloomington, IN | Indiana | IU |
| North Texas | Iowa | Kinnick Stadium, Iowa City, IA | Iowa | Iowa |
| Mercer | #15 Auburn | Jordan-Hare Stadium, Auburn, AL | Auburn | Auburn |
| Purdue | Missouri | Memorial Stadium/Faurot Field, Columbia, MO | Mizzou | Missouri |
| Army | #8 Ohio State | Ohio Stadium, Columbus, OH | Ohio St | OSU |
| Oregon State | #21 Washington St | Martin Stadium, Pullman, WA | Wash St | Wazzu |
| Tulane | #2 Oklahoma | Memorial Stadium , Norman, OK | Oklahoma | Oklahoma |
| North Carolina A&T | Charlotte | McColl-Richardson Field, Charlotte, NC | Charlotte | Charlotte |
| Colgate | Buffalo | UB Stadium, Buffalo, NY | Buffalo | Buffalo |
| Bethune-Cookman | Florida Atlantic | FAU Football Stadium, Boca Raton, FL | FAU | FAU |
| Kent State | Marshall | Joan C. Edwards Stadium, Huntington, WV | Marshall | Marshall |
| Colorado State | #1 Alabama | Bryant-Denny Stadium, Tuscaloosa, AL | Alabama | Alabama |
| #12 LSU | Mississippi State | Davis Wade Stadium, Starkville, MS | LSU | LSU |
| Southern Mississippi | Louisiana Monroe | Malone Stadium, Monroe, LA | USM | USM |
| Southern | UT San Antonio | Alamodome, San Antonio, TX | UTSA | UTSA |
| Louisiana Tech | Western Kentucky | L.T. Smith Stadium, Bowling Green, KY | WKU | WKU |
| Oregon | Wyoming | War Memorial Stadium , Laramie, WY | Ducks | Oregon |
| Arkansas-Pine Bluff | Arkansas State | Centennial Bank Stadium, Jonesboro, AR | Arkansas St | Ark St |
| Idaho | Western Michigan | Waldo Stadium, Kalamazoo, MI | WMU | WMU |
| Alabama A&M | South Alabama | Ladd-Peebles Stadium, Mobile, AL | USA | USA |
| Tulsa | Toledo | Glass Bowl, Toledo, OH | Toledo | Toledo |
| Appalachian State | Texas State | Bobcat Stadium , San Marcos, TX | App St | App ST |
| Idaho State | Nevada | Mackay Stadium, Reno, NV | Nevada | Nevada |
| Georgia State | #5 Penn State | Beaver Stadium, University Park, PA | Penn St | Penn St |
| Margin of Victory | 54 | 42 | ||
| Samford | #13 Georgia | Sanford Stadium, Athens, GA | Georgia | Georgia |
| #18 Kansas State | Vanderbilt | Vanderbilt Stadium, Nashville, TN | Kansas St | Kansas State |
| Kentucky | South Carolina | Williams-Brice Stadium, Columbia, SC | South Carolina | SC |
| Bowling Green | Northwestern | Ryan Field, Evanston, IL | NW | NW |
| #3 Clemson | #14 Louisville | Papa John’s Cardinal Stadium, Louisville, KY | Clemson | Clemson |
| Rice | Houston | TDECU Stadium, Houston, TX | Houston | Houston |
| Troy | New Mexico State | Aggie Memorial Stadium, Las Cruces, NM | Troy | Troy |
| Cincinnati | Miami (OH) | Yager Stadium, Oxford, OH | Miami (OH) | Cincy |
| Arizona State | Texas Tech | Jones AT&T Stadium, Lubbock, TX | Texas Tech | TTU |
| Texas | #4 USC | Los Angeles Memorial Coliseum, Los Angeles, CA | USC | USC |
| Fresno State | #6 Washington | Husky Stadium, Seattle, WA | Washington | Washington |
| San José State | Utah | Rice-Eccles Stadium, Salt Lake City, UT | Utah | Utah |
| #19 Stanford | San Diego State | Qualcomm Stadium, San Diego, CA | Stanford | Stanford |
| Ole Miss | California | Memorial Stadium , Berkeley, CA | Ole Miss | Ole Miss |
| Gameday Guest Picker (Louisville) | Tom Jackson | Jennifer Lawrence | ||
| Total Points this season | 133 | 138 |
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