Joe DiTullio and Rob Doerger make college football picks for week 11, which includes all games involving FBS teams. There have been plenty of touchdowns, sacks and big plays with more to come. Here are the picks for the week:
| Away | Home | Location | Rob | Joe |
| Akron | Miami (OH) | Yager Stadium, Oxford, OH | Akron | Miami |
| Bowling Green | Buffalo | UB Stadium, Buffalo, NY | Buffalo | Buffalo |
| Kent State | Western Michigan | Waldo Stadium, Kalamazoo, MI | W. Mich | WMU |
| Toledo | Ohio | Peden Stadium, Athens, OH | Toledo | Toledo |
| Eastern Michigan | Central Michigan | Kelly/Shorts Stadium, Mount Pleasant, MI | C. Mich | CMU |
| Ball State | Northern Illinois | Huskie Stadium, DeKalb, IL | NIU | NIU |
| Georgia Southern | Appalachian State | Kidd Brewer Stadium, Boone, NC | App St | App St |
| North Carolina | Pittsburgh | Heinz Field, Pittsburgh, PA | Pitt | Pitt |
| Temple | Cincinnati | Nippert Stadium, Cincinnati, OH | Cincy | UC |
| #9 Washington | Stanford | Stanford Stadium, Stanford, CA | Washington | Washington |
| BYU | UNLV | Sam Boyd Stadium, Las Vegas, NV | UNLV | BYU |
| #12 Michigan State | #13 Ohio State | Ohio Stadium, Columbus, OH | OSU | OSU |
| Rutgers | #14 Penn State | Beaver Stadium, University Park, PA | Penn St | PSU |
| #15 Oklahoma State | #21 Iowa State | Jack Trice Stadium, Ames, IA | OK State | Ok State |
| Connecticut | #18 UCF | Spectrum Stadium, Orlando, FL | UCF | UCF |
| Margin of Victory | 41 | 33 | ||
| Does the winner leave with the Civil ConFLiCT trophy? | No | No | ||
| #23 NC State | Boston College | Alumni Stadium , Chestnut Hill, MA | BC | NC State |
| Arkansas | #24 LSU | Tiger Stadium , Baton Rouge, LA | LSU | LSU |
| Duke | Army | Michie Stadium, West Point, NY | Army | Army |
| Texas Tech | Baylor | AT&T Stadium, Arlington, TX | Texas Tech | TTU |
| Louisiana | Ole Miss | Vaught-Hemingway Stadium, Oxford, MS | Ole Miss | Ole Miss |
| Florida | South Carolina | Williams-Brice Stadium, Columbia, SC | SC | SC |
| Indiana | Illinois | Memorial Stadium , Champaign, IL | Indiana | Indiana |
| Nebraska | Minnesota | TCF Bank Stadium, Minneapolis, MN | Nebraska | Nebaska |
| #17 Virginia Tech | Georgia Tech | Bobby Dodd Stadium, Atlanta, GA | VT | VT |
| Middle Tennessee | Charlotte | McColl-Richardson Field, Charlotte, NC | MTSU | MTSU |
| Wake Forest | Syracuse | Carrier Dome, Syracuse, NY | Syracuse | Cuse |
| #1 Georgia | #10 Auburn | Jordan-Hare Stadium, Auburn, AL | Georgia | Georgia |
| Florida State | #4 Clemson | Memorial Stadium , Clemson, SC | Clemson | Clemson |
| #20 Iowa | #8 Wisconsin | Camp Randall Stadium, Madison, WI | Wisconsin | Wisconsin |
| Virginia | Louisville | Papa John’s Cardinal Stadium, Louisville, KY | Louisville | Louisville |
| Michigan | Maryland | Maryland Stadium, College Park, MD | Michigan | Michigan |
| West Virginia | Kansas State | Bill Snyder Family Stadium, Manhattan, KS | WVU | WVU |
| SMU | Navy | Navy-Marine Corps Memorial Stadium, Annapolis, MD | Navy | Navy |
| Florida Atlantic | Louisiana Tech | Joe Aillet Stadium, Ruston, LA | FAU | Louisiana Tech |
| Southern Mississippi | Rice | Rice Stadium, Houston, TX | So Miss | USM |
| #11 USC | Colorado | Folsom Field, Boulder, CO | USC | USC |
| Maine | UMass | Fenway Park, Boston, MA | Umass | Umass |
| Georgia State | Texas State | Bobcat Stadium , San Marcos, TX | Ga St | Ga State |
| San Jose State | Nevada | Mackay Stadium, Reno, NV | Nevada | Nevada |
| Kentucky | Vanderbilt | Vanderbilt Stadium, Nashville, TN | Vandy | Vandy |
| Troy | Coastal Carolina | Brooks Stadium, Conway, SC | Troy | Troy |
| Arkansas State | South Alabama | Ladd-Peebles Stadium, Mobile, AL | Ark St | Ark State |
| UTEP | North Texas | Apogee Stadium, Denton, TX | UNT | UNT |
| #19 Washington State | Utah | Rice-Eccles Stadium, Salt Lake City, UT | Wash St | Wazzu |
| Kansas | Texas | Royal Texas Memorial Stadium, Austin, TX | Texas | Texas |
| Western Kentucky | Marshall | Joan C. Edwards Stadium, Huntington, WV | Marshall | Marshall |
| #2 Alabama | #16 Mississippi State | Davis Wade Stadium, Starkville, MS | Alabama | Alabama |
| Purdue | #25 Northwestern | Ryan Field, Evanston, IL | NW | NW |
| UAB | UT San Antonio | Alamodome, San Antonio, TX | UAB | UAB |
| Tulane | East Carolina | Dowdy-Ficklen Stadium, Greenville, NC | ECU | ECU |
| New Mexico | Texas A&M | Kyle Field, College Station, TX | A&M | TAMU |
| Old Dominion | Florida Intl | FIU Stadium, Miami, FL | FIU | FIU |
| Tennessee | Missouri | Memorial Stadium/Faurot Field, Columbia, MO | Mizzou | Missouri |
| #3 Notre Dame | #7 Miami | Hard Rock Stadium, Miami, FL | ND | ND |
| #6 TCU | #5 Oklahoma | Memorial Stadium , Norman, OK | Oklahoma | Oklahoma |
| Arizona State | UCLA | Rose Bowl, Pasadena, CA | Arizona St | ASU |
| Oregon State | Arizona | Arizona Stadium, Tucson, AZ | Arizona | Zona |
| Wyoming | Air Force | Falcon Stadium, Usaf Academy, CO | AFA | AFA |
| Boise State | Colorado State | CSU Stadium, Fort Collins, CO | Colorado St | CSU |
| Fresno State | Hawai’i | Aloha Stadium, Honolulu, HI | Fresno | Fresno |
| Gameday Guest Picker (Miami) | The Rock | Ray Lewis |
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