The college basketball season has started! There are plenty of big games that will be picked this year. Here are college basketball picks week of November 27.
Note: These are moneyline picks. This article will be updated weekly.
| Away | Home | Joe |
| New Hampshire | UConn | UConn |
| Mississippi State | Georgia Tech | Miss State |
| Miami | Kentucky | Miami |
| Eastern Illinois | Kansas | Kansas |
| Nicholls | Baylor | Baylor |
| Texas Southern | Purdue | Purdue |
| Southern | Marquette | Marquette |
| Cal State Baskersfield | Gonzaga | Gonzaga |
| Clemson | Alabama | Alabama |
| Saint Joseph’s | Villanova | Villanova |
| Buffalo | James Madison | James Madison |
| Tennessee | North Carolina | Tennessee |
| Texas A&M | Virginia | TAMU |
| Colorado | Colorado State | Colorado |
| Duke | Arkansas | Duke |
| Liberty | Florida Atlantic | FAU |
| Arkansas Pine-Bluff | Oklahoma | Oklahoma |
| Creighton | Oklahoma State | Oklahoma State |
| Texas State | Texas | Texas |
| Houston | Xavier | Houston |
| Purdue | Northwestern | Purdue |
| UConn | Kansas | UConn |
| Fresno State | BYU | BYU |
| Notre Dame | Miami | Miami |
| Marquette | Wisconsin | Marquette |
| Florida State | UNC | UNC |
| Duke | Georgia Tech | Duke |
| Colgate | Arizona | Arizona |
| Illinois | Rutgers | Illinois |
| UNC Wilmington | Kentucky | Kentucky |
| Northwestern State | Baylor | Baylor |
| Charleston | Florida Atlantic | FAU |
| Colorado State | Washington | Washington |
| USC | Gonzaga | Gonzaga |
| Keystone | James Madison | James Madison |
| Creighton | Nebraska | Creighton |
| Southern | Mississippi State | Miss State |
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