The college basketball season has started! There are plenty of big games that will be picked this year. Here are college basketball picks week of November 25.
Note: These are moneyline picks. There will be a new picks article every week.
| Away | Home | Joe |
| Maui Invitational Winner | UConn | |
| Battle 4 Atlantis Winner | Gonzaga | |
| Memphis | UConn | UConn |
| Maryland Eastern Shore | Arkansas | Arkansas |
| South Carolina | Xavier | Xavier |
| Auburn | Iowa State | Auburn |
| Little Rock | Illinois | Illinois |
| Dayton | UNC | UNC |
| San Diego State | Creighton | Creighton |
| Oregon | Texas A&M | Texas A&M |
| Western Kentucky | Kentucky | Kentucky |
| Houston | Alabama | Houston |
| Kansas | Duke | Kansas |
| Louisville | Indiana | Indiana |
| New Orleans | Baylor | Baylor |
| West Virginia | Gonzaga | Gonzaga |
| UT Martin | Tennessee | Tenn |
| Texas A&M | Creighton | Creighton |
| Alabama State | Cincinnati | Cincinnati |
| Davidson | Arizona | Arizona |
| Stonehill | Marquette | Marquette |
| Rutgers | Alabama | Alabama |
| Notre Dame | Houston | Houston |
| Florida | Wake Forest | Florida |
| Purdue | NC State | Purdue |
| Arkansas | Illinois | Illinois |
| BYU | Ole Miss | BYU |
| Miss State | UNLV | Miss State |
| Georgia State | Kentucky | Kentucky |
| Seattle | Duke | Duke |
| Chicago State | Wisconsin | Wisconsin |
| Western Carolina | Marquette | Marquette |
| Furman | Kansas | Kansas |
| Maryland Eastern Shore | UConn | UConn |
| South Carolina State | Xavier | Xavier |
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