The college basketball season has started! There are plenty of big games that will be picked this year. Here are college basketball picks week of January 15.
Note: These are moneyline picks. There will be a new picks article every week.
| Away | Home | Joe |
| Villanova | Marquette | Marquette |
| Purdue | Indiana | Purdue |
| Florida | Tennessee | Tenn |
| TCU | Cincinnati | TCU |
| Baylor | Kansas State | Baylor |
| Saint Louis | Dayton | Dayton |
| Kansas | Oklahoma State | Kansas |
| Wisconsin | Penn State | Wisconsin |
| Iowa State | BYU | Iowa State |
| Utah State | New Mexico | New Mexico |
| Mississippi State | Kentucky | UK |
| Creighton | UConn | UConn |
| Ole Miss | LSU | Ole Miss |
| West Virginia | Oklahoma | Oklahoma |
| Louisville | North Carolina | UNC |
| Texas Tech | Houston | Houston |
| Auburn | Vanderbilt | Auburn |
| USC | Arizona | Zona |
| USF | Memphis | Memphis |
| Wichita State | Florida Atlantic | FAU |
| Illinois | Michigan | Illinois |
| Indiana | Wisconsin | Wisconsin |
| Baylor | Texas | Texas |
| Marquette | St. John’s | St. John’s |
| Creighton | Seton Hall | Seton Hall |
| Rhode Island | Dayton | Dayton |
| Oklahoma | Cincinnati | Oklahoma |
| Purdue | Iowa | Purdue |
| UCF | Houston | Houston |
| Alabama | Tennessee | Tennessee |
| Iowa State | TCU | TCU |
| North Carolina | Boston College | UNC |
| Kansas | West Virginia | Kansas |
| UCLA | Arizona | Zona |
| Fresno State | Utah State | Utah State |
| BYU | Texas Tech | Texas Tech |
| Georgia | Kentucky | UK |
| UConn | Villanova | UConn |
| Pittsburgh | Duke | Duke |
| Ole Miss | Auburn | Auburn |
| Memphis | Tulane | Memphis |
| Rutgers | Illinois | Illinois |
| FAU | UTSA | FAU |
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